Potential peripheral biomarkers associated with the emergence and presence of posttraumatic stress disorder symptomatology: A systematic review

AM Sbisa; K Madden; C Toben; AC McFarlane; L Dell; E Lawrence-Wood

Journal article

Potential peripheral biomarkers associated with the emergence and presence of posttraumatic stress disorder symptomatology: A systematic review

AM Sbisa, K Madden, C Toben, AC McFarlane, L Dell, E Lawrence-Wood

Psychoneuroendocrinology | Published : 2023

DOI: 10.1016/j.psyneuen.2022.105954

Abstract

Background: Evidence suggests posttraumatic stress disorder (PTSD) involves an interplay between psychological manifestations and biological systems. Biological markers of PTSD could assist in identifying individuals with underlying dysregulation and increased risk; however, accurate and reliable biomarkers are yet to be identified. Methods: A systematic review following the PRISMA guidelines was conducted. Databases included EMBASE, MEDLINE, and Cochrane Central. Studies from a comprehensive 2015 review (Schmidt et al., 2015) and English language papers published subsequently (between 2014 and May 2022) were included. Forty-eight studies were eligible. Results: Alterations in neuroendocrine..

View full abstract

University of Melbourne Researchers

Alyssa Sbisa Author

Kelsey Madden Author

Lisa Dell Author

Ellie Lawrence-Wood Author

Related Projects (1)

TRANSLATING SCIENCE INTO BETTER POSTTRAUMATIC MENTAL HEALTH

Trauma is responsible for a significant amount of mental health problems worldwide. Increasing disasters, violence, and war lead to much tra..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This research was funded by a National Health and Medical Research Council (NHMRC) Program Grant (APP1073041) -Translating Science into Better Posttraumatic Mental Health.